学术讨论
academic discussion
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Chlorogenic acid inhibits glioblastoma growth through repolarizating macrophage from M2 to M1 phenotype
Chlorogenic acid inhibits glioblastoma growth through repolarizating macrophage from M2 to M1 phenotype2017.01.05本文研究了绿原酸（CHA）通过将肿瘤相关巨噬细胞从促肿瘤的M2表型极化为抗肿瘤的M1表型，从而抑制胶质母细胞瘤生长的机制。研究发现，CHA通过促进STAT1信号通路激活和抑制STAT6信号通路激活来调节巨噬细胞的极化状态。